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A recent study conducted by Stanford University and J. Hopkins University has shown that artificial human heart tissue underwent significant weakening during just one month on the ISS. Changes at the molecular and genetic level that mimic aging were identified.
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Using induced pluripotent stem cells, the scientists created a “heart on a chip” and placed it in a chamber to monitor contractions. The tissue’s contraction weakened by almost half after a dozen days in space, while the ground samples remained stable.